Surge Dose

Double the efficacy In half the time

This technology looks fabulous. The idea of being able to significantly improve efficacy in a reduced time frame would be a major breakthrough for formulation technology as well as providing obvious clinician and user benefits.

- Professor Mike Roberts

Who are we?

Imaginot Pty Ltd is based in Brisbane, Australia, and is a leader in innovative formulation technology for rapid dissolution and absorption potentially applicable to a wide range of drugs. Imaginot has developed a novel technology – Surge Dose® – which enhances drug delivery performance to achieve effective plasma levels faster and more consistently, typically “twice the efficacy in half the time”.


The problem with variable absorption

achieves

  • ultra-fast activated pH-controlled drug dissolution
  • fast absorption under a wide range of physiological conditions
  • drug absorption profiles more like oral solution or injection than a solid dosage form


sdFormulation
  • After 5 minutes

    SurgeDose® tablets disintegrate significantly faster than standard tablets. From the SD formulation the drug commences dissolution and emptying with co-administered water passing into the small intestine where it can be absorbed.

  • After 20 minutes

    SurgeDose® ® tablets have dissolved and drug has emptied from the stomach with significant absorption completed. With standard tablets, drug is still in the stomach and has not reached the small intestine.

marketedFormulation

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SurgeDose® provides

  • a paradigm shift in novel drug formulation with improved PK
  • for paracetamol, lornoxicam (marketed) and diclofenac
  • and many other drugs
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SurgeDose® delivers

  • twice the efficacy in half the time
  • a novel game-changing approach with clear proprietary advantages
  • reduction in slow Tmax associated with lower efficacy and slow response
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SurgeDose® drives

  • rapid absorption and distribution through ultra-rapid, activated, pH controlled dissolution optimized for each drug
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SurgeDose® increases

  • probability of complete reimbursement and higher prices based on demonstrable improved comparative efficacy
  • brand differentiation exciting physicians and patients
  • patent protection

Twice the efficacy in half the time – through a cascade of events